RAB26

Protein-coding gene in the species Homo sapiens

RAB26

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
2G6B

Identifiers

Aliases

RAB26, V46133, member RAS oncogene family

External IDs

OMIM: 605455; MGI: 2443284; HomoloGene: 25655; GeneCards: RAB26; OMA:RAB26 - orthologs

Gene location (Human)

Chr.	Chromosome 16 (human)^[1]

Band	16p13.3	Start	2,140,803 bp^[1]
Band	16p13.3	End	2,154,165 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 17 (mouse)^[2]

Band	17\|17 A3.3	Start	24,746,215 bp^[2]
Band	17\|17 A3.3	End	24,753,184 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

right hemisphere of cerebellum

cerebellar vermis

right frontal lobe

putamen

nucleus accumbens

caudate nucleus

anterior cingulate cortex

Brodmann area 9

parotid gland

body of pancreas

Top expressed in

dentate gyrus of hippocampal formation granule cell

superior frontal gyrus

primary visual cortex

otic vesicle

parotid gland

hippocampus proper

Region I of hippocampus proper

lacrimal gland

temporal lobe

prefrontal cortex

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	nucleotide binding GTP binding protein binding GMP binding GTPase activity
Cellular component	intrinsic component of plasma membrane Golgi membrane Golgi apparatus transport vesicle membrane membrane cytoplasmic vesicle endosome plasma membrane synaptic vesicle secretory granule membrane anchored component of synaptic vesicle membrane
Biological process	protein transport exocrine system development regulated exocytosis Golgi to plasma membrane protein transport vesicle docking involved in exocytosis protein secretion regulation of exocytosis intracellular protein transport Rab protein signal transduction regulation of protein catabolic process at presynapse, modulating synaptic transmission
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


25837


328778

Ensembl


ENSG00000167964


ENSMUSG00000079657

UniProt


Q9ULW5


Q504M8

RefSeq (mRNA)


NM_001308053 NM_014353


NM_177375

RefSeq (protein)


NP_001294982 NP_055168


NP_796349

Location (UCSC)

Chr 16: 2.14 – 2.15 Mb

Chr 17: 24.75 – 24.75 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Ras-related protein Rab-26 is a protein that in humans is encoded by the RAB26 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167964 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000079657 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Seki N, Yoshikawa T, Hattori A, Miyajima N, Muramatsu M, Saito T (Oct 2000). "cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region". J Hum Genet. 45 (5): 309–14. doi:10.1007/s100380070023. PMID 11043516.
^ "Entrez Gene: RAB26 RAB26, member RAS oncogene family".

Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j.1471-4159.2006.03836.x. PMC 2239266. PMID 16696853.
Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. Bibcode:2004Natur.432..988M. doi:10.1038/nature03187 (inactive 2024-04-27). PMID 15616553.{{cite journal}}: CS1 maint: DOI inactive as of April 2024 (link)
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yoshie S, Imai A, Nashida T, Shimomura H (2000). "Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland". Histochem. Cell Biol. 113 (4): 259–63. doi:10.1007/s004180000130. PMID 10857477. S2CID 39587270.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.