| IL6 |
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| 사용 가능한 구조 |
|---|
| PDB | 동원체 검색: PDBe RCSB |
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| PDB ID 코드 목록 |
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4O9H, 1ALU, 1IL6, 1P9M, 2IL6, 4CNI, 4J4L, 4NI7, 4NI9, 4ZS7 |
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| 식별자 |
|---|
| 다른 이름 | IL6, BSF2, HGF, HSF, IFNB2, IL-6, BSF-2, CDF, IFN-beta-2, interleukin 6 |
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| 외부 ID | OMIM: 147620 MGI: 96559 HomoloGene: 502 GeneCards: IL6 |
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| RNA 발현 패턴 |
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| Bgee | | 인간 | 쥐(동원체) |
|---|
| 최상위 발현 | - cartilage tissue
- 대정맥
- 쓸개
- 왼자궁관
- 생식샘
- 민무늬근
- mucosa of urinary bladder
- upper lobe of left lung
- 랑게르한스섬
- 고환
|
| | 최상위 발현 | - 배
- stroma of bone marrow
- 주머니배
- endothelial cell of lymphatic vessel
- spermatocyte
- spermatid
- 과립구
- lumbar spinal ganglion
- 랑게르한스섬
- atrioventricular valve
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| | 추가 참조 발현 데이터 |
|
|---|
| BioGPS |  | | 추가 참조 발현 데이터 |
|
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| 유전자 온톨로지 |
|---|
| 분자 함수 | - 사이토카인 활성
- growth factor activity
- interleukin-6 receptor binding
- 단백질 결합
| | 세포 성분 | - 세포밖공간
- interleukin-6 receptor complex
- 세포 바깥쪽
- endoplasmic reticulum lumen
| | 생물학적 과정 | - regulation of angiogenesis
- positive regulation of translation
- platelet activation
- 체액성 면역 반응
- defense response to virus
- response to peptidoglycan
- neuron projection development
- defense response to Gram-positive bacterium
- negative regulation of fat cell differentiation
- positive regulation of peptidyl-serine phosphorylation
- positive regulation of leukocyte chemotaxis
- positive regulation of T cell proliferation
- positive regulation of interleukin-6 production
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of acute inflammatory response
- inflammatory response
- negative regulation of collagen biosynthetic process
- positive regulation of MAPK cascade
- hepatic immune response
- monocyte chemotaxis
- positive regulation of DNA-binding transcription factor activity
- 세포자멸사 과정의 하향조절
- 조골세포 분화의 상향조절
- 전사인자 NF-kB 활성의 상향조절
- acute-phase response
- 면역반응
- regulation of vascular endothelial growth factor production
- positive regulation of chemokine production
- negative regulation of lipid storage
- neutrophil mediated immunity
- positive regulation of smooth muscle cell proliferation
- positive regulation of type B pancreatic cell apoptotic process
- response to glucocorticoid
- defense response to Gram-negative bacterium
- positive regulation of cell population proliferation
- positive regulation of apoptotic process
- positive regulation of B cell activation
- 번역 후 변형
- 신호전달 수용체 활성의 조절
- positive regulation of tyrosine phosphorylation of STAT protein
- neutrophil apoptotic process
- negative regulation of cell population proliferation
- positive regulation of gene expression
- endocrine pancreas development
- negative regulation of bone resorption
- positive regulation of transcription, DNA-templated
- positive regulation of transcription by RNA polymerase II
- glucagon secretion
- cellular response to hydrogen peroxide
- cellular response to lipopolysaccharide
- T-helper 17 cell lineage commitment
- positive regulation of T-helper 2 cell cytokine production
- negative regulation of interleukin-1-mediated signaling pathway
- cytokine-mediated signaling pathway
- interleukin-6-mediated signaling pathway
- positive regulation of receptor signaling pathway via JAK-STAT
- 신호전달
| | 출처: Amigo / QuickGO |
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| 동원체 |
|---|
| 종 | 인간 | 쥐 |
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| 앙트레 | | |
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| 앙상블 | | |
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| 유니프롯 | | |
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| RefSeq (mRNA) | |
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NM_000600
NM_001318095
NM_001371096 |
| |
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| RefSeq(단백질) | |
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NP_000591
NP_001305024
NP_001358025 |
| |
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| 위치(UCSC) | Chr 7: 22.73 – 22.73 Mb | Chr 5: 30.22 – 30.22 Mb |
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| PubMed 검색 | [3] | [4] |
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| 위키데이터 |
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